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In the chloroplast stroma, the oxygenase activity of RUBISCO leads to the formation of 2P-glycolate, which is converted to glycolate

ROS derived from the Nox subtypes Nox1, Nox2, and Nox4 lead to vascular dysfunction in diabetic retinopathy, and Nox5-derived ROS increase the incidence of abdominal aortic aneurysms in diabetic patients [16, 17]

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(December 2019)