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Description
This is also supported by the fact that besides KIT and PTEN , mutations in PI3K and AKT homologous of PI3K-AKT-mTOR are scarce (4.8% PIK3CA , 3.8% PIK3CG , and 4.8% AKT3 ) ( 105)
Agitation causes cavitation (microscopic bubble formation) and shear forces that denature proteins

10.1016/j.freeradbiomed.2014.12.006

1989), which can turn into thrombosis

Nevertheless, individual differences in effectiveness and the necessity of combining the said strategy with a healthy lifestyle remain valid for optimal results
