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10.1016/j.cbi.2009.11.028 206 UpadhyayG.KumarA.SinghM

Brooks PJ, Zakhari S

In vulnerable tissues - particularly liver parenchyma, striated muscle, and myocardium - excess lipid burden initiates both cell death pathways and inflammatory responses (209)

In the case of autoimmune thyroid disease, removing the thyroid with a thyroidectomy eliminates thyroid antibodies, as there is nothing left to attack

If you miss a piece, put one in the wrong spot, or fail to connect them properly, the final structure is compromised