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Hyperglycemia and RAAS in the Kidney High glucose levels in the proximal tubule can cause increased reabsorption of glucose, sodium and water, favored by the upregulation of SGLT2 activity and expression of Na-K-2Cl cotransporter, acquaporin-2, and urea transporters, as reported in diabetic patients (32)

Materials and methods This systematic review and meta-analysis was written according to the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines [8]

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N Engl J Med (2019) 381(9):84151

Endometriosis-focused contraception guidance continues to view hormonal contraception as a cornerstone for symptom control and prevention of recurrence, especially with long-acting progestogen options