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Glucagon also contributes to energy homeostasis by promoting satiety through vagal signaling to brainstem nuclei and by increasing resting energy expenditure through facultative thermogenesis in brown adipose tissue, skeletal muscle, and through promotion of WAT browning [22]

The weight loss ranges of the two treatment groups were -6.9 kg (-7%) and -9.7 kg (-9.6%), respectively

This review article is based on previously published studies and publicly available data

One honest caveat from the data: because the Phase 2 curve had not clearly plateaued by the end of the study, the full ceiling of the effect is genuinely not yet known that is one of the questions the Phase 3 TRIUMPH program is designed to answer

Be sure to read the instructions for your medication carefully, and reach out to your provider if you have any questions