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The drug has a long half-life, which means it can be administered monthly or less frequently, giving the drug the potential to improve adherence and long-term weight control, according to Jay Bradner, executive vice president of research and development at Amgen
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Patients may increase fiber intake, consume more artificial sweeteners (particularly sugar alcohols), or dramatically reduce fat consumptionall of which can affect stool consistency

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doi: 10.1016/j.orcp.2019.03.003 73 YinQ
