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Van Heertum R

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An electrostatic scaffold of salt bridges at the binding interface between GLP-1R and semaglutide analogues In 2021 as mentioned above, a manually designed V-R exchange [43] was introduced into the backbone of semaglutide for an improve GLP-1R ECD affinity

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Genetic variants within or near the GLP1R gene associated with BMI or HbA1c at genome-wide significance were used for primary analyses
