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Opsonophagocytic antibodies have been linked to protection against other intracellular bacteria as well as M.tb, including Staphylococcus aureus , Escherichia coli , Salmonella , and Shigella ( Regarding opsonophagocytosis, antibody-mediated phagocytosis is followed by phagolysosome fusion to digest antibody-bound complexes/microorganisms